IRIS Toxicological Review of Tetrachloroethylene (Perchloroethylene)
Dee Lewis on Jul 19th 2008
National Center for Environmental
IRIS Toxicological Review of Tetrachloroethylene (Perchloroethylene) (External Review Draft)
Federal Register Notices
Contacts
by phone at: 703-347-8561
by fax at: 703-347-8691
by email at: nceadc.comment@epa.gov
Notice
EPA announces the release of the Toxicological Review of Tetrachloroethylene (External Review Draft) in the June 26, 2008, Federal Register Notice. This draft assessment is provided for public viewing and comment. Public comments received on the Toxicological Review within 90 days after the release of the FRN will be provided to the external peer reviewers for their consideration.
The date and location of the external peer review meeting will be provided in a separate FR Notice.
EPA is conducting a peer review of the scientific basis supporting the human health hazard and dose-response assessment of tetrachloroethylene that will appear on the Integrated Risk Information System (IRIS) database. Peer review is meant to ensure that science is used credibly and appropriately in derivation of the toxicological characterization and dose-response assessments.
This draft health assessment addresses both non-cancer and cancer human health effects that may result from chronic exposure to tetrachloroethylene (also called “Perchloroethylene” or “Perc”) . This is an update of an existing assessment posted on IRIS in 1988. This draft Toxicological Review includes a chronic Reference Concentration (RfC) and carcinogenicity assessment, which are not currently available on IRIS, as well as an update of the 1988 IRIS Reference Dose (RfD).
Full Document http://cfpub.epa.gov/ncea/cfm/recordisplay.cfm?deid=192423
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